Readout Automation and GUI for an Experimental μ-cantilever-based MEMS Biosensor
In 2011, as an undergraduate researcher in mechanical engineering, I worked on a MEMS biosensor project at Koç University’s Optical Microsystems Laboratory.
OML’s multi-analyte MEMS biosensor uses an array of coated μ-cantilevers that shift their resonant frequencies upon analyte mass accretion, allowing the detection of analyte concentrations. The cantilevers are magnetically actuated and their resonant frequencies are observed via interferometric optical readout. The remote and wireless chip is intended for use within a portable device.
I designed and implemented a custom GUI and mechanism for setting up characterization experiments by directly manipulating the position of the chip relative to the laser beam. The system then traverses the μ-cantilever array and collects data without supervision.
O. Cakmak, N. Kilinc, E.Ermek, A. Mostafazadeh, C. Elbuken, G.G. Yaralioglu, H. Urey “LoC Sensor Array Platform for Real-Time Coagulation Measurements ” accepted to IEEE MEMS 2014.
O. Cakmak, N. Kilinc, E.Ermek, G.G. Yaralioglu, H. Urey “MEMS Based Blood Plasma Viscosity Sensor Without Electrical Connections” in IEEE Sensors 2013, Baltimore, Maryland, USA, November 2013.
N Kilinc, O Cakmak, A Kosemen, E Ermek, S Ozturk, Y Yerli, ZZ Ozturk, H Urey, “A Voc Sensor Based on Micromechanical Cantilever Functionalized with ZnO Nanorods” The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTas 2013), Freiburg, Germany, October 2013.
Cakmak O, Elbuken C., Ermek E., Mostafazadeh A., Alaca B.E., Urey H., “Microcantilever Based Disposable Viscosity Sensor for Serum and Blood Plasma Measurements” Methods, 63 (2013) 225-232.
O. Çakmak, Ç. Elbüken, E. Ermek, S. Bulut, Y. Kılınç, I. Barış, H. Kavaklı, E. Alaca, H. Ürey, ” MEMS biosensor for blood plasma viscosity measurements” New Biotechnology, 29, Supplement S162-S163, 2012. (also published as Proceedings of the European Congress on Biotechnolgy Conference)
Erman Timurdogan, Natali Ozber, Sezin Nargul, Serhat Yavuz, M. Salih Kilic, I. Halil Kavakli, Hakan Urey, and B. Erdem Alaca, ” Detection of human K-opioid antibody using microresonators with integrated optical readout,” Biosensors and Bioelectronics, Vol. 26, pp. 195-201, 2010
A. Ozturk, H. I. Ocakli, N. Ozber, H. Kavakli, H. Urey, E. Alaca, “A magnetically actuated resonant mass sensor with integrated optical readout,” Phot. Tech.. Lett., Vol. 20, 1905-1907, 2008